There are 10 types of childhood trauma measured in the ACE Study. Five are personal — physical abuse, verbal abuse, sexual abuse, physical neglect, and emotional neglect. Each type of trauma counts as one.
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An anal fissure is a split in the anal skin, just inside the anus, usually towards the back. The pain of an anal fissure feels like being cut with glass when you have your bowels open and afterwards. It is worse when you have had a hard bowel motion.
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Judith knew how to spot bowel cancer because her husband was dying of it but a needless delay by her GP means it could kill her too. Soul mates: Judith husband's Ken was dying from bowel cancer and then she discovered she also had the disease. Ken, a former engineer, died a year ago.
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A Spigelian hernia or lateral ventral hernia is a hernia through the Spigelian fasciawhich is the aponeurotic layer between the rectus abdominis muscle medially, and the semilunar line laterally. These are generally interparietal hernias, meaning that they do not lie below the subcutaneous fat but penetrate between the muscles of the abdominal wall ; therefore, there is often no notable swelling. Spigelian hernias are usually small and therefore risk of strangulation is high.
Metrics details. Cancer-specific hypermethylation of promoter CpG islands is common during the tumorigenesis of colon cancer. Although associations between certain genetic aberrations, such as BRAF mutation and microsatellite instability, and the CpG island methylator phenotype CIMPhave been found, the mechanisms by which these associations are established are still unclear. Using differential methylation hybridization on oligonucleotide microarrays representing 32, CpG-rich regions, we identified 1, regions with differential methylation between colorectal tumor and paired normal colon.
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PURPOSE: A randomized, double-blind, controlled study was conducted to investigate the efficacy of oral calcium dobesilate therapy in treating acute attacks of internal hemorrhoids. METHODS: Twenty-nine well-documented adult patients with first- or second-degree internal hemorrhoids were treated with calcium dobesilate for two weeks, while 16 patients received only a high-fiber diet to serve as control. Both symptoms and anoscopic inflammation were scored on a scale from 0 to 2 before T 0 and two weeks after treatment T 2.