Correspondence Address : Dr. Paget's disease of the breast is a rare type of cancer of the nipple—areola complex and that is often associated with an underlying in situ or invasive carcinoma. Diagnosis and treatment of Paget's disease is controversial.
A core needle biopsy uses a long, hollow tube to extract a sample of tissue. Here, a biopsy of a suspicious breast lump is being done. The sample is sent to a laboratory for testing.
As a patient, the stage and grade of your breast cancer tumor will guide your treatment and have an impact on prognosis. Learn what staging and grade mean, as well as how they are calculated. The pathologic stage of breast cancer is a measure of how advanced a patient's tumor is.
Benign breast conditions also called benign breast diseases are noncancerous disorders of the breast. They can occur in both women and men. There are many types of benign breast conditions. Your health care provider may use the term fibrocystic change to describe a range of benign breast conditions.
When your breast was biopsied, the samples taken were studied under the microscope by a specialized doctor with many years of training called a pathologist. The pathologist sends your doctor a report that gives a diagnosis for each sample taken. Information in this report will be used to help manage your care.
Your physicians will perform several tests on your tumor tissue to provide specific information about your individual cancer. Your pathology report is one of the resources containing information about your tumor. This report will help guide your healthcare team in planning the appropriate treatment for you.
Breast diseases make up a number of conditions. The most common symptoms are a breast massbreast painand nipple discharge. A majority of breast diseases are noncancerous.
Mitochondria are the intracellular organelles responsible for ATP production to meet the energy demands 1. Generally, there are several hundred to 1, mitochondria in a human cell and 2—10 copies of mitochondrial DNA mtDNA in a human mitochondrion to compose the mitochondrial network 2. The amount of mtDNA copies in a human cell is highly variable, depending on the cell type and the surrounding pathophysiological conditions, and usually is positively correlated to the energy demands 3.
A more recent article on common breast problems is available. See related patient information handout on breast painwritten by Amy S. Weichel, D.
Most women experience breast changes at some time. Your age, hormone levels, and medicines you take may cause lumps, bumps, and discharges fluids that are not breast milk. If you have a breast lump, pain, discharge or skin irritation, see your health care provider. Minor and serious breast problems have similar symptoms.